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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '624f0b4564e548fdf1973ea3e5cbf6742b5906244dc3c3c68c3beaa74fda271a' 
  AND token = 'r9atF7/N6tLtOGmKz/44UuGTefmpFL6bjbJGTYSCe3w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}