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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec6630766cdc8211e9faf265b0267184fbd7a738653c66556d7cc7e39b24b2d9' 
  AND token = 'sPqubG4bsZv9w+5QlV6CuA0w9Et6cYhMSOKFrS3s09g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}