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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '343784620a1db268abf2a7d1a235054e3630933e25872bc7500c3133bd4dba64' 
  AND token = 'aaGG3RWQ33DDEAalwqqH0FZoTh2SQgJ6kNDYLlOIF3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}