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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcf83c33102cd5df7b07786d4c175fbcd1a460b78434ef8145d349261e0b3abf' 
  AND token = 'w2wTFGEsGQUFT1g4heDoHJH4MRh3TaEIbCYkvEi1n18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}