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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2486a8bef9c1172d6db72d58416786ae5768e4260bd665c944e77e1bfcf8b6db' 
  AND token = 'Ma2QdoqkPMvUUsbMfjv1NZxU/kCS4wv7qMz46ZyWzgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}