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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20dba4dac42ada640bece53386e4bf1636b62f3d398a91e93837289d3b22bf6f' 
  AND token = 'AcRt42fk8hnS0keIbMionpI0zCmbOaPHHQW8vhomeME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}