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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a3d2ed5f07b53682f0f39c52fb57e2637944d2707327fd54669cddd1dd29341' 
  AND token = 's3ePLw46HWN2EjvUTtSfewGigd6vKjqCISc+mhpcPyg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}