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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54ca6b1a755bced30e16a9949fa18c1a21cd9db97bd2ccb7bacf73e3015de4d2' 
  AND token = 'I4B1kb2qSaBkDcIDiTJlEellwkX8g51oTfB50KduRk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}