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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c66f9d806559339c25256c738302a8cffc2767824e86fd187575fdfbd1f7c828' 
  AND token = 'QOJHaNi85Yf30fDfz7G3XhT1pW+/OPYR4EeEa5OQ1uE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}