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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d715600e0cc9136436cb93adde22ec52ce2f200fb66d06ef6e483e0f6e1af60' 
  AND token = 'fRCYauc90h6MC978NamP3dQO9b0vBWESgXIgI8ev8Yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}