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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9be7aaeec85997d2d2f9efea1c3ee3e6119bd6e53e93849cc80fe8503eab1160' 
  AND token = 'NXTHToL+FXg6SKQuus2NzJV80OGdYzyZzBFXGqM+Wys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}