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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38d438bf6a8076c354f075034ac6eb821260570f1de4e4274ba0b770878801b7' 
  AND token = 'ePZxAOsPo9Qpg0Ks5b6te14sCbffW5Kl9kWcywkrwTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}