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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cddb37b6694cd5b0bdec001f44dd4956a65fd71b86c3ff5ac5607166abdf1f8' 
  AND token = '/xQiRc83S5jtFMqts4rp7v7n3dSgOVWbu5QhVo1rbmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}