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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e99de9e2c7f4f89a4714d5224c70236fabcef88528963b5bb54ab0c172e4921' 
  AND token = 'DtHnEKr6LKoyODkobpbVBjkyvXTqhtphficn0jFEmyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}