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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cd27b48abd0e7f58bc36205c3de070babecd7b0072ba35f5834d4cdf859f340' 
  AND token = 'TGA+d2mX0qKTjPtZltB3O2JkydG49VuZxWaj3CS0MuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}