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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29b8746174ae017106f1212506aba769224441a2d52c52e16a9d3aadb4288a7a' 
  AND token = '3m7IrOkfQU5QqSJihZ+c+yQrVgHTG85xmBz7OXW46aY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}