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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e6f2cb4619da996864d6d146a832f832eb671cff0bb231c63ffa79cc80f3b46' 
  AND token = '1v60sOXux3du7QaIBvF9JZwQ7XGAAuDnyXh7IK/NkPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}