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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4d4d9e5ab02f97bf59202ef1d2f47debafe4a23b59491eb688ad5bbca7bf208' 
  AND token = 'CTx0aAWER3DaoP3BQ9WPdhjznzla3VXFT97WatEzw18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}