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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d061a8898e95a29c0c52b2a5dd132b004c60951d2ef92defad95a65db272265' 
  AND token = 'zV+ZKJ+QmyvmSzfWhCvyubxb9nH2ClcPmyRavDyrLqw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}