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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ef36ee22855c6d271a0253dc841cf089a0cd9484c8925adb8f07971107cbd0e' 
  AND token = 'FM6fGrSqT7yHjr6RzvPgPaH8IjsRadWtO5NbO7Q8pYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}