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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24130ffb29d140fa889a4e051ec23178c0fe2abeef45cd8d97b56c571649d62c' 
  AND token = '166lrSuGe6qjTuyOPPPO5kiiJ06+CfVYKb4PzFS1aic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}