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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d275cbad8efde96c899a9a60cb153a961b845c101b0677791611004f1a80006' 
  AND token = '1zToJg57lSUhbhtAkwteuJ9QDrORHlLmTCFy9qeue5k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}