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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9abd8d6ed80f5d0f4b03887fc54cacc6225cc2e9329aa111b21511f5d4292ce8' 
  AND token = 'zQ9E1lZ+BMOQ86IKHvqsQBI7OzydNQk1HDJkFWmNlgM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}