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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7ca8ce34bcfd901c0776de509609394092155327cafe57d1b713bfb2fa42a99' 
  AND token = '7bbmKha5Nsvu5/XmPZxtkiNragvsKRjA12g/3RA0vbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}