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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '886b7ce4225c4241faeb300aec0e738565b3d62d82e7b7066321a93b9a027c74' 
  AND token = 'AMZzGP72hz7vcaOueCOlJT1C/OpV7yZdefmIwP1L3O8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}