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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b8bbb24d3966431a9ebe701bee1dfe0e89d330b708d71f8eee3e1fd64d7bcd9' 
  AND token = 'oFp6ecMuXtYD9cZSRiZijZybjHe6TLKmgwQyRNkgnc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}