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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b43feec2417ca981f65cad2aed5973c5592912a87d2a9b93aa7afed30800d97' 
  AND token = 'dbqLMEhztcK/yDOz3gIJkDLm/7uvn5tdvNqNj0nfIic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}