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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '003a07244a3e6044afb81eb97c0dce58134d42cf3e11f9e7dde3a070bdadf81d' 
  AND token = 'OpyizdYpF3UKKAJRUL0h0sI2ua6a7jYOlNU2DuBwv+E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}