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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b52262f1e49c56dadee29a3d1d31d77131e0c88e3cca4bb40cd665239337411' 
  AND token = 'Dt8v65qUopGvSduwz74+NKHx6PwJAUZ4VWNxmixvf3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}