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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a40d467dd8107c7805e2794a93e9daa18bea29976592fdd8c6b7b1e9bb48aa63' 
  AND token = 'UpxVZlhFbDOmzdBan28p2/OAV8ovlVkgW/HxlmgBEdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}