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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b4439568e0127e1623b8acb3dfbf0a4b829a5e11d7d1c80ae49ed3a997261cc' 
  AND token = 'ioR+etcW/1qBk7Wyj3aNM+g4gYUG+ioQXv01fsZ8paA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}