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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c54d967b19ae89c9241b8d1a0a11e85459ed5e5d339eb9cd212603007fb9e23f' 
  AND token = 'vHH4b1COtaMj1AZCTIfKuC9g6bWb6L121bLnDvXnrGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}