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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e2305d299b8d5678f3dda286490aa1c76c1995fb211807735cb0cadde3e7b18' 
  AND token = 'PTC2x4v/Jh0uTDGXbys5MA7lc+64DkAIPyXwL0R+fKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}