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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6af4dfc07c2419998a92b9bf5bd4e5eef27af97793a76f957735553a43565e1' 
  AND token = 'Y/oGL3VmPWbJ9zwTm4aejbpbBJ4vflW9CjQXbbJ3nso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}