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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39ab896c42dd12b1633e66caea2de0f1a568163ab52bde95f0487b33af2e6ff1' 
  AND token = 'k0XwSxF5fWCJTSblIIG04HY+iC51j0u8szJ0MdFB8UY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}