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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48accde38cdf3119023f9f5d4790619de21cf3046356a0f2397c19e91d74d90a' 
  AND token = 'eR/l1VJTvVHF7HOK65NKjWFGIIma6Ht7I/Vim7aXJPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}