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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8ea725689b33199a9ff531fc03ebd9878aa398e7d566f11aa093493efc3a282' 
  AND token = 'Nn4HKMtWyUdznXazln8rZd77OieqxJ4hsGK+Lwc12MQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}