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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59ca33c3f2569d9c248c6cf3f6838c53d09c8cc0276a92a9669cda733d263601' 
  AND token = 'L6dcNF8r+SH0PXZvQW1eZ1UG5KThhh/SSdMS1WifZd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}