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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13878fb2d95fe44e2b05606591d6fcab3b9029728805a47438770d3c5bc7f6f5' 
  AND token = 'oDRgnrXharS4xJxIjDS7IEUuB0s7D60f/fvBZQSS8z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}