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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6427b0905143646c30bf275a25bc526f4d8cd96fc5bd68f447053f648de44ea' 
  AND token = '/ort4qbNnovOzA4nyeA5KI31zG3sgzbPeTpCz54Cxic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}