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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7afe9eea150f371f1d17d16495616b4e161a09ece00cf333d3bada3b46c0a18' 
  AND token = 'BChljr+48CNUh5wf3jHFTZp4VbbnqofUwAm0Caen0+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}