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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ffa8e213b110b4b350ce1639f892507fe183980435402f8b05f950d2a9ae911' 
  AND token = '4O3Qoq0MOQFauOfqihj5eTzg+O2Y5stxcmq7NOLMNII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}