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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '036488b02eff00a8a873da81bc333c0e7181345db40e4bf14abf4b9e80797202' 
  AND token = '5i3fVeSxrRyAPnfEU32e6z5OwMMj40Aprrg6mMw9i2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}