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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd72086c927f586651e7d78c5730ed009b439e70dd48ae0e44ec217b3d847a500' 
  AND token = 'kKne2xsbWmFugKLFHZv/hDOHKBCTSw7Xv+bq7bv+2I8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}