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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9375d6616778b841258d69914922b85e98fd6ce70aba5a7248121bc5b288078b' 
  AND token = 'ectLQV/VFKx29SQoadotmX8HkMrCH4Hl1VgG0tWSWjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}