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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbbd81949ce2d3ad90cf979e5341addfb5c759dba66a45ca7104d516fa7f646b' 
  AND token = 'Ujs7kEOzvWgSLPLHFuVWHr/y9RJeyt4ZzMF7Z26er/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}