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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '342dff46627a1c10b88d08c64e5ad0dd403fc8c002216fe8090d16beab02057f' 
  AND token = 'R1eSXwxLyScEOeA2DSn5K0lHwOokdXl67a0gAmS8QNA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}