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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bdf675bf2d1accebd45cd5222fab7a46835da24d593f9b8f707b1a5f1b64202' 
  AND token = 'hWKRyMNR3Na0TuRac2S8pJL6RIb67PR8rpEr4EOQhRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}