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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80c81f3f5b4f94630f8b29ace60379b7f20013c9fc5a19dd97c911cf9789c109' 
  AND token = 'eG8no3F92vC4Z6Tq9gRnsD60mXStFWAIwf5FDHiOq4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}