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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '403beaac08422b9b8b2fee7cb63a19013d6969b3a2ec990e6351d219d7c0af2d' 
  AND token = 'ruEmKwAKdrSg9pjhCQKsXY26ULqDsFF4vk5SpQW5NKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}